Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24840897 | 1.00 | CFTR (0.38) | CFTRGOPCNPSR1GAACYP2C9 | |
| SCHEMBL24794778 | 1.00 | CFTR (0.38) | CFTRGOPCNPSR1GAACYP2C9 | |
| SCHEMBL19003668 | 1.00 | CFTR (0.38) | CFTRGOPCNPSR1GAACYP2C9 | |
| SCHEMBL9488195 | 0.81 | OPRM1 (0.36) | CFTRGOPCOPRM1OPRK1OPRL1 | |
| SCHEMBL1698175 | 0.81 | CA1 (0.37) | CFTRGOPCOPRM1OPRK1OPRL1 | |
| SCHEMBL6627945 | 0.73 | NPSR1 (0.32) | CFTRGOPCNPSR1GAACYP2C9 | |
| Bicarbonate SCHEMBL9350627 | 0.72 | AKR1C1 (0.41) | LMNAAKR1C1CYP1A2HTTOPRM1 | |
| SCHEMBL4143463 | 0.69 | CFTR (0.50) | CFTRGOPCNPSR1GAACYP2C9 | |
| SCHEMBL30463421 | 0.69 | CFTR (0.50) | CFTRGOPCNPSR1GAACYP2C9 | |
| SCHEMBL7915738 | 0.69 | CFTR (0.50) | CFTRGOPCNPSR1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023276966-A1 | PHARMACEUTICAL COMPOSITION CONTAINING FULLERENE INCLUDING METAL IONS | 国立大学法人大阪大学 | 2023-01-05 | — | — | WO | disclosed |
| US-20210164005-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | UNIVERSITY OF DELAWARE (US) | 2021-06-03 | — | — | US | disclosed |
| US-10875840-B2 | Methods for inducing bioorthogonal reactivity | UNIVERSITY OF DELAWARE (US) | 2020-12-29 | — | — | US | disclosed |
| WO-2017106427-A1 | METHODS FOR INDUCING BIOORTHOGONAL REACTIVITY | FOX JOSEPH (US) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10875840-B2 | Methods for inducing bioorthogonal reactivity | CBR1, CBR3, DUOX1 | CFTR 4844/4885GOPC 1546/4885NPSR1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.