SCHEMBL19003768

SCHEMBL19003768

N#Cc1ccc(-c2ccc3c4c(ccc(-c5ccc(C#N)cc5)c24)-c2c-3c(-c3ccccc3)c3ccccc3c2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
AR P10275 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
ABCG2 Q9UNQ0 2/20 0.37
GRM5 P41594 1/20 0.37
CYP11B2 P19099 1/20 0.37
SLC22A12 Q96S37 1/20 0.36
METAP2 P50579 1/20 0.36
LRRK2 Q5S007 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19003779 0.92 ADORA2A (0.41) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL14073020 0.90 ALDH1A1 (0.37) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL13170658 0.89 ATM (0.40) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL4073469 0.89 ATM (0.40) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL19003773 0.89 KIF11 (0.53) ATMALDH1A1PTGDR2CYP11B2
SCHEMBL10038776 0.88 ATM (0.39) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL13170737 0.88 ATM (0.39) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL13170691 0.88 ATM (0.39) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL13170742 0.88 ATM (0.39) ATMALDH1A1TSHRMEN1KMT2A
SCHEMBL13191983 0.87 ATM (0.39) ATMALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017104767-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME TDK株式会社 2017-06-22 WO disclosed