SCHEMBL19003776

SCHEMBL19003776

N#Cc1ccc(-c2ccc(-c3ccc4c5c(cccc35)-c3c-4c(-c4ccccc4)c4ccccc4c3-c3ccccc3)cc2)cc1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 3/20 0.41
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
THRB P10828 1/20 0.41
MCL1 Q07820 4/20 0.40
MAOB P27338 5/20 0.39
MAOA P21397 4/20 0.39
HPGD P15428 3/20 0.37
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
BCL2 P10415 1/20 0.36
CYP2C9 P11712 2/20 0.35
S1PR1 P21453 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GALR3 O60755 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19003772 0.95 ALDH1A1 (0.43) ALDH1A1KDM4ELMNAHTTRXFP1
SCHEMBL21671483 0.90 XDH (0.42) ALDH1A1KDM4ELMNAHTTRXFP1
SCHEMBL30169931 0.90 MCL1 (0.41) ALDH1A1KDM4EMCL1MAOBMAOA
SCHEMBL21643669 0.90 MCL1 (0.41) ALDH1A1KDM4EMCL1MAOBMAOA
SCHEMBL13170655 0.89 MCL1 (0.37) ALDH1A1KDM4EMCL1MAOBMAOA
SCHEMBL21671475 0.88 MAOA (0.37) ALDH1A1KDM4ELMNAHTTRXFP1
SCHEMBL30169967 0.88 KDM4E (0.38) ALDH1A1KDM4EMCL1MAOBMAOA
SCHEMBL13170679 0.88 KDM4E (0.38) ALDH1A1KDM4EMCL1MAOBMAOA
SCHEMBL13192365 0.87 XDH (0.42) ALDH1A1KDM4ELMNAHTTRXFP1
SCHEMBL24067706 0.86 CYP11B1 (0.37) ALDH1A1KDM4ELMNAHTTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017104767-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME TDK株式会社 2017-06-22 WO disclosed