Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 16/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443428 | 0.83 | GLS (0.71) | GLSALDH1A1POLB | |
| SCHEMBL7607443 | 0.80 | GLS (1.00) | GLSALDH1A1POLB | |
| SCHEMBL14987653 | 0.77 | GLS (0.83) | GLS | |
| SCHEMBL19003803 | 0.75 | GLS (0.63) | GLSALDH1A1POLB | |
| SCHEMBL14987005 | 0.75 | GLS (0.54) | GLS | |
| SCHEMBL19003805 | 0.72 | GLS (0.58) | GLSALDH1A1POLB | |
| SCHEMBL14987395 | 0.72 | GLS (0.81) | GLSALDH1A1POLB | |
| SCHEMBL21443340 | 0.72 | GLS (0.62) | GLS | |
| SCHEMBL14987396 | 0.71 | GLS (0.79) | GLSALDH1A1POLB | |
| SCHEMBL14038120 | 0.70 | ALDH1A1 (0.57) | GLSALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975048-B2 | Composition of 1,3,4-selenadiazole containing compounds with pharmacological activity | HANGZHOU JENNIFER BIOTECH CO LTD (CN) | 2021-04-13 | — | — | US | disclosed |
| WO-2017101793-A1 | 1, 3, 4-SELENADIAZOLE COMPOUNDS WITH PHARMACOLOGICAL ACTIVITY | HANGZHOU JENNIFER BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975048-B2 | Composition of 1,3,4-selenadiazole containing compounds with pharmacological activity | GPX4, GPX1, SELENOI | GLS 54/4885ALDH1A1 1109/4885POLB 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.