SCHEMBL1900391

SCHEMBL1900391

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(N)O)O2)c(=S)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
TK1 P04183 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210837 0.89 POLB (0.63) POLBTK1
SCHEMBL3204369 0.84 POLB (0.65) POLBTK1
SCHEMBL5982157 0.83 TK1 (0.60) TK1
SCHEMBL11875571 0.83 TK1 (0.60) TK1
SCHEMBL114559 0.83 TK1 (0.60) TK1
SCHEMBL15187541 0.83 TK1 (0.60) TK1
SCHEMBL114560 0.83 TK1 (0.60) TK1
SCHEMBL11874785 0.83 TK1 (0.60) TK1
SCHEMBL8349986 0.81 POLB (0.63) POLBTK1
SCHEMBL6291957 0.81 POLB (0.66) POLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102124020-B self-avoiding molecular recognition system for DNA amplification BENNER STEVEN ALBERT 2015-04-29 CN disclosed
EP-2321332-B1 SELF-AVOIDING MOLECULAR RECOGNITION SYSTEMS IN DNA AMPLIFICATION BENNER STEVEN A (US) 2013-03-27 EP disclosed
CN-102124020-A Self-avoiding molecular recognition system for DNA amplification ALBERT BENNER STEVEN 2011-07-13 CN disclosed
EP-2321332-A1 SELF-AVOIDING MOLECULAR RECOGNITION SYSTEMS IN DNA AMPLIFICATION Benner, Steven A. (US) 2011-05-18 EP disclosed
WO-2010021702-A9 SELF-AVOIDING MOLECULAR RECOGNITION SYSTEMS IN DNA AMPLIFICATION BENNER STEVEN ALBERT (US) 2010-05-06 WO disclosed
WO-2010021702-A1 SELF-AVOIDING MOLECULAR RECOGNITION SYSTEMS IN DNA AMPLIFICATION BENNER STEVEN ALBERT (US) 2010-02-25 WO disclosed