SCHEMBL210837

SCHEMBL210837

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(N)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.63
TK1 P04183 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8349986 0.91 POLB (0.63) POLBTK1
SCHEMBL19101649 0.91 POLB (0.66) POLBTK1
SCHEMBL17514032 0.91 POLB (0.66) POLBTK1
SCHEMBL28399790 0.91 POLB (0.66) POLBTK1
SCHEMBL1764557 0.90 TK1 (0.65) POLBTK1
SCHEMBL7537922 0.89 POLB (0.61) POLBTK1
SCHEMBL1900391 0.89 POLB (0.52) POLBTK1
SCHEMBL8425023 0.89 POLB (0.61) POLBTK1
SCHEMBL316664 0.88 POLB (0.67) POLBTK1
SCHEMBL646741 0.88 POLB (0.67) POLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 680 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666879-B Templated nanometer conjugate NORTHWEST UNIVERSITY (US) 2016-02-24 CN claimed
CN-102666879-A Templated nanoconjugates UNIV NORTHWESTERN 2012-09-12 CN claimed
EP-2494075-A2 TEMPLATED NANOCONJUGATES Northwestern University (US) 2012-09-05 EP claimed
WO-2011053940-A2 TEMPLATED NANOCONJUGATES NORTHWESTERN UNIVERSITY (US) 2011-05-05 WO claimed
WO-2008080060-A2 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS GEORGIA STATE UNIVERSITY (US) 2008-07-03 WO claimed
US-12447142-B2 Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2025-10-21 US disclosed
EP-4600742-A2 INCREASING EFFICIENCY OF PHOTOCHEMICAL REACTIONS ON SUBSTRATES Centrillion Technologies, Inc. (US) 2025-08-13 EP disclosed
US-20250250565-A1 OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES ALPHA ANOMERIC SAS (FR) 2025-08-07 US disclosed
EP-3351632-B1 STRUCTURALLY-ENHANCED MIRNA INHIBITOR S-TUD UNIV TOKYO (JP) 2025-07-16 EP disclosed
US-20250205671-A1 Increasing Efficiency Of Photochemical Reactions On Substrates CENTRILLION TECHNOLOGIES, INC. 2025-06-26 US disclosed
WO-2025108237-A1 LIPID COMPOUND, NUCLEIC ACID CONJUGATE AND USE THEREOF 施能康生物科技有限公司 2025-05-30 WO disclosed
CN-120025369-A Lipid compound, nucleic acid conjugate and application thereof 施能康生物科技有限公司 2025-05-23 CN disclosed
WO-1994015946-A1 SYNTHESIS OF DIMMER BLOCKS AND THEIR USE IN ASSEMBLING OLIGONUCLEOTIDES HYBRIDON, INC. (US) 1994-07-21 WO disclosed
US-5252723-A Using sulfur, non-aromatic tertiary amine and solvent, producing nucleotide multimer GEN-PROBE, INC. (US) 1993-10-12 US disclosed
EP-0542822-A1 VIRAL (HIV) GROWTH INHIBITION MEDICAL RESEARCH COUNCIL (GB) 1993-05-26 EP disclosed
WO-1992004358-A1 METHOD AND REAGENT FOR SULFURIZATION OF ORGANOPHOSPHOROUS COMPOUNDS GEN-PROBE INCORPORATED (US) 1992-03-19 WO disclosed
WO-1992002228-A1 VIRAL (HIV) GROWTH INHIBITION MEDICAL RESEARCH COUNCIL (GB) 1992-02-20 WO disclosed
EP-0424819-A1 Reversible modification of biological compounds for detection, separation and purification thereof MILLIPORE CORPORATION (US) 1991-05-02 EP disclosed
WO-1990011322-A2 METHOD AND REAGENT FOR SULFURIZATION OF ORGANOPHOSPHOROUS COMPOUNDS GEN-PROBE INCORPORATED (US) 1990-10-04 WO disclosed
EP-0386987-A1 Method and reagent for sulfurization of organophosphorous compounds GEN-PROBE INCORPORATED (US) 1990-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12447142-B2 Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy CTSE, CTSB, ATG4B POLB 600/4885TK1 1449/4885
US-20250205671-A1 Increasing Efficiency Of Photochemical Reactions On Substrates TYR, PCNA, DNMT1 POLB 266/4885TK1 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.