Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | TNNI3 | P19429 | 2/20 | 1.00 |
| ▸ | TNNT2 | P45379 | 2/20 | 1.00 |
| ▸ | TNNC1 | P63316 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sennoside B SCHEMBL19004132 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL14478776 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL15216902 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL19235654 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL17430774 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL23685626 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL441194 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL17131971 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside A,B SCHEMBL20822082 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E | |
| Sennoside B SCHEMBL14353400 | 1.00 | USP2 (1.00) | USP2HKDC1L3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10959979-B2 | Small molecules against cancer | BIOKINE THERAPEUTICS LTD. (IL) | 2021-03-30 | — | — | US | disclosed |
| US-20200268709-A1 | SMALL MOLECULES AGAINST CANCER | BIOKINE THERAPEUTICS LTD. (IL) | 2020-08-27 | — | — | US | disclosed |
| US-10646465-B2 | Small molecules against cancer | BIOKINE THERAPEUTICS LTD. (IL) | 2020-05-12 | — | — | US | disclosed |
| US-20190240188-A1 | SMALL MOLECULES AGAINST CANCER | ALONBIO LTD. (IL) | 2019-08-08 | — | — | US | disclosed |
| WO-2017103931-A1 | SMALL MOLECULES AGAINST CANCER | BIOKINE THERAPEUTICS LTD. (IL) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10959979-B2 | Small molecules against cancer | CCL2, CXCR2, CCL5 | USP2 2894/4885HKDC1 1238/4885L3MBTL1 1727/4885 |
| US-10646465-B2 | Small molecules against cancer | CCL2, CXCR2, CCL5 | USP2 2894/4885HKDC1 1238/4885L3MBTL1 1727/4885 |
| US-20200268709-A1 | SMALL MOLECULES AGAINST CANCER | CCL2, CXCR2, CCL5 | USP2 2894/4885HKDC1 1238/4885L3MBTL1 1727/4885 |
| US-20190240188-A1 | SMALL MOLECULES AGAINST CANCER | CCL2, CXCR2, CCL5 | USP2 2894/4885HKDC1 1238/4885L3MBTL1 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.