Sennoside B

Sennoside B

SCHEMBL19235654

O=C(O)c1cc(O)c2c(c1)C(C1c3cc(C(=O)O)cc(O)c3C(=O)c3c(OC4OC(CO)C(O)C(O)C4O)cccc31)c1cccc(OC3OC(CO)C(O)C(O)C3O)c1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 1.00
HKDC1 Q2TB90 3/20 1.00
L3MBTL1 Q9Y468 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
TNNI3 P19429 2/20 1.00
TNNT2 P45379 2/20 1.00
TNNC1 P63316 2/20 1.00
MEN1 O00255 2/20 1.00
CYP3A4 P08684 2/20 1.00
MAPK1 P28482 2/20 1.00
RECQL P46063 2/20 1.00
KMT2A Q03164 2/20 1.00
NPC1 O15118 1/20 1.00
RAB9A P51151 1/20 1.00
LMNA P02545 1/20 1.00
GLA P06280 1/20 1.00
THRB P10828 1/20 1.00
HPGD P15428 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sennoside B SCHEMBL19004132 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL14478776 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL15216902 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL17430774 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL19004127 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL23685626 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL441194 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL17131971 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside A,B SCHEMBL20822082 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E
Sennoside B SCHEMBL14353400 1.00 USP2 (1.00) USP2HKDC1L3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119700111-A Method for testing human body behavior ability and cognition ability in anoxic tunnel environment 天津大学 2025-03-28 CN claimed
CN-119602007-A High-current bus connecting terminal and preparation method thereof 中国长江电力股份有限公司 2025-03-11 CN claimed
CN-119528679-A Norbornene separation and purification method and system 中国石油化工股份有限公司 2025-02-28 CN claimed
CN-116239446-B Separation and recovery process of byproduct mixed alcohol of polyester device 上海华峰新材料研发科技有限公司 2025-02-14 CN claimed
CN-118439762-A Treatment system and treatment method for high-concentration hemicellulose deep processing wastewater 唐山三友集团兴达化纤有限公司 2024-08-06 CN claimed
CN-117603092-B Method for separating acetonitrile-water azeotrope by mixed solvent extraction and rectification 周口师范学院 2024-06-07 CN claimed
CN-117603092-A Method for separating acetonitrile-water azeotrope by mixed solvent extraction and rectification 周口师范学院 2024-02-27 CN claimed
CN-110950733-B Separation device and method for preparing olefin gas from methanol 中国石油天然气股份有限公司 2023-09-26 CN claimed
CN-116775885-A Cross-domain aspect emotion classification method based on pretraining fine adjustment 山西财经大学 2023-09-19 CN claimed
CN-114907491-B Multi-epitope peptide, helicobacter pylori octavalent multi-epitope vaccine and preparation method 中国科学院西北生态环境资源研究院 2023-06-16 CN claimed
CN-116002970-A Optical glass, preform, and optical element 株式会社小原 2023-04-25 CN claimed
CN-115872406-A Hydrogen fluoride wastewater resource utilization system device and method in photovoltaic industry 深圳市超纯环保股份有限公司 2023-03-31 CN claimed
US-12570863-B2 Catalyst-containing polymer coatings formed by chemical grafting CATALYTIC INDUSTRIAL GROUP, INC. (US) 2026-03-10 US disclosed
CN-120161101-A AEM water electrolysis membrane electrode failure diagnosis method 国网浙江省电力有限公司电力科学研究院 2025-06-17 CN disclosed
CN-120137157-A Hyperbranched polymer dispersing agent for lithium ion battery anode slurry and preparation method thereof 联泓(江苏)新材料研究院有限公司 2025-06-13 CN disclosed
CN-120118973-A Acetaldehyde dehydrogenase activity detection kit, detection method and application thereof 浙江大学长三角智慧绿洲创新中心 2025-06-10 CN disclosed
CN-111326080-B Display device 乐金显示有限公司 2022-05-13 CN disclosed
US-11241404-B2 Method, composition and package for bowel cleansing SHAVER WILLIAM A (US) 2022-02-08 US disclosed
WO-2017133517-A1 PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF 四川海思科制药有限公司 2017-08-10 WO disclosed
CN-106999973-A System and method for discharging edible material 阿甘芳香和精细化工有限公司 2017-08-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570863-B2 Catalyst-containing polymer coatings formed by chemical grafting FTO, PCNA, MPO USP2 2196/4885HKDC1 1483/4885L3MBTL1 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.