Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.62 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004878 | 0.90 | TBK1 (0.62) | TBK1IKBKECCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL18985648 | 0.89 | TBK1 (0.61) | TBK1IKBKECCNT1CDK9 | |
| SCHEMBL18985814 | 0.86 | TBK1 (0.79) | TBK1 | |
| SCHEMBL19004994 | 0.84 | TBK1 (0.66) | TBK1IKBKE | |
| SCHEMBL19005192 | 0.84 | TBK1 (0.71) | TBK1IKBKE | |
| SCHEMBL18985932 | 0.84 | TBK1 (0.80) | TBK1IKBKE | |
| Hydrochloric Acid SCHEMBL20720923 | 0.83 | TBK1 (0.70) | TBK1IKBKE | |
| SCHEMBL19004876 | 0.83 | NPSR1 (0.52) | TBK1IKBKECCNT1CDK9 | |
| SCHEMBL19005014 | 0.82 | POLB (0.51) | TBK1IKBKECCNT1CDK9 | |
| SCHEMBL18985947 | 0.82 | TBK1 (0.65) | TBK1IKBKECCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |