Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004936 | 0.84 | ALPI (0.36) | ALPIALPGPLAAGABRDGABRA1 | |
| SCHEMBL6920523 | 0.84 | ALPI (0.36) | ALPIALPGPLAAGABRDGABRA1 | |
| SCHEMBL20732654 | 0.81 | MPO (0.31) | PTGS1PTGS2 | |
| SCHEMBL18985808 | 0.77 | — | — | |
| SCHEMBL23762954 | 0.76 | CRHR1 (0.38) | ALPIALPGPLAAGABRDGABRA1 | |
| SCHEMBL6936894 | 0.76 | CRHR1 (0.46) | ALPIALPGPLAACRHR1JAK2 | |
| SCHEMBL19005064 | 0.73 | ALPI (0.35) | ALPIALPGPLAACRHR1LMNA | |
| SCHEMBL18985666 | 0.71 | PIK3CD (0.44) | — | |
| SCHEMBL13393548 | 0.71 | ALDH1A1 (0.43) | ALPIALPGPLAACRHR1LMNA | |
| SCHEMBL23762953 | 0.71 | CRHR1 (0.37) | ALPIALPGPLAAGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |