Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19331754 | 0.90 | DDB1 (0.44) | ALDH1A1KDM4EHPGDDDB1CRBN | |
| SCHEMBL12320881 | 0.88 | DDB1 (0.42) | ALDH1A1KDM4EDDB1CRBNNR1H2 | |
| SCHEMBL19341990 | 0.87 | DDB1 (0.39) | ALDH1A1KDM4EGLAHPGDRECQL | |
| SCHEMBL31511525 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KDM4EGLAHPGDRECQL | |
| SCHEMBL16825886 | 0.85 | DDB1 (0.43) | ALDH1A1KDM4EHPGDDDB1CRBN | |
| SCHEMBL4739542 | 0.84 | PARP1 (0.45) | KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL656014 | 0.82 | DDB1 (0.44) | ALDH1A1KDM4EHPGDDDB1CRBN | |
| SCHEMBL31732367 | 0.81 | DDB1 (0.41) | ALDH1A1KDM4EGLAHPGDRECQL | |
| SCHEMBL183637 | 0.80 | MAPT (0.46) | ALDH1A1KDM4EGLAHPGDRECQL | |
| SCHEMBL29450286 | 0.80 | MAPT (0.46) | ALDH1A1KDM4EGLAHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025081019-A1 | KIF MODULATOR COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |