Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005989 | 0.91 | HDAC1 (0.37) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL18987192 | 0.87 | CYP19A1 (0.44) | HTR1ASLC6A4HDAC1HDAC2MEN1 | |
| SCHEMBL19005918 | 0.83 | HTR1A (0.38) | HTR1ASLC6A4MEN1KMT2ANPSR1 | |
| SCHEMBL19005957 | 0.82 | HDAC1 (0.36) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL19005969 | 0.81 | CYP19A1 (0.45) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL18987395 | 0.81 | CHRM4 (0.37) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL18987197 | 0.80 | HDAC1 (0.36) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL18987410 | 0.79 | CYP3A4 (0.41) | HDAC1HDAC2MEN1KMT2ANPSR1 | |
| SCHEMBL18987304 | 0.79 | HDAC1 (0.39) | HDAC1HDAC2MEN1KMT2ASLC5A1 | |
| SCHEMBL19005985 | 0.79 | HDAC1 (0.39) | HDAC1HDAC2MEN1KMT2ASLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |