Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987197 | 0.96 | HDAC1 (0.36) | HDAC1HDAC2TUBB4ATUBBTUBA3C | |
| SCHEMBL18987365 | 0.87 | CYP19A1 (0.44) | HDAC1HDAC2TUBB4ATUBBTUBA3C | |
| SCHEMBL18987706 | 0.86 | CTNNB1 (0.41) | HDAC1HDAC2TUBB4ATUBBTUBA3C | |
| SCHEMBL19005959 | 0.83 | KMT2A (0.39) | HDAC1HDAC2MEN1KMT2ATSHR | |
| SCHEMBL19005979 | 0.82 | HTT (0.36) | MEN1KMT2ANPSR1GAA | |
| SCHEMBL19005956 | 0.82 | HTR1A (0.36) | HDAC1HDAC2CTNNB1WNT3AMEN1 | |
| SCHEMBL18987379 | 0.81 | CYP19A1 (0.46) | HDAC1HDAC2TUBB4ATUBBTUBA3C | |
| SCHEMBL996935 | 0.80 | TUBB1 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL996932 | 0.80 | TUBB1 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19005989 | 0.80 | HDAC1 (0.37) | HDAC1HDAC2MEN1KMT2ASLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |