Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18987199 | 0.87 | TSHR (0.35) | KMT2ATSHRHDAC1HDAC2PDE4A | |
| SCHEMBL18987197 | 0.86 | HDAC1 (0.36) | KMT2ATSHRMEN1HDAC1HDAC2 | |
| SCHEMBL18987365 | 0.85 | CYP19A1 (0.44) | KMT2ATSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL18987706 | 0.84 | CTNNB1 (0.41) | KMT2AMEN1HDAC1HDAC2 | |
| SCHEMBL19005957 | 0.83 | HDAC1 (0.36) | KMT2ATSHRMEN1HDAC1HDAC2 | |
| SCHEMBL19005992 | 0.81 | HDAC1 (0.39) | KMT2ATSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL19005960 | 0.74 | REN (0.34) | KMT2AHDAC1HDAC2PDE4APDE4B | |
| SCHEMBL18987379 | 0.73 | CYP19A1 (0.46) | KMT2ATSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL19005961 | 0.72 | REN (0.36) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18987377 | 0.72 | REN (0.36) | TSHRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |