Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 2/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005959 | 0.87 | KMT2A (0.39) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18987377 | 0.86 | REN (0.36) | TSHRCITLARS1PDE4APDE4B | |
| SCHEMBL19005961 | 0.86 | REN (0.36) | TSHRCITLARS1PDE4APDE4B | |
| SCHEMBL18987197 | 0.82 | HDAC1 (0.36) | TSHRHDAC1HDAC2KMT2A | |
| SCHEMBL18987365 | 0.81 | CYP19A1 (0.44) | TSHRHDAC1HDAC2KMT2A | |
| SCHEMBL18987706 | 0.81 | CTNNB1 (0.41) | HDAC1HDAC2KMT2A | |
| SCHEMBL19005960 | 0.79 | REN (0.34) | PDE4APDE4BPDE4CPDE4DAAK1 | |
| SCHEMBL19005957 | 0.79 | HDAC1 (0.36) | TSHRHDAC1HDAC2KMT2A | |
| SCHEMBL19006008 | 0.75 | HDAC1 (0.36) | TSHRHDAC1HDAC2KMT2A | |
| SCHEMBL18987392 | 0.73 | LARS1 (0.35) | TSHRCITLARS1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | claimed |
| WO-2017103637-A1 | DIPHENYLPROPANE COMPOUNDS AND THEIR CYTOTOXIC ACTIVITY | BLIRT S.A. (PL) | 2017-06-22 | — | — | WO | disclosed |