SCHEMBL19007325

SCHEMBL19007325

Cc1cc(C)cc(N2CCOCC2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.66
KDM4E B2RXH2 2/20 0.60
MAPT P10636 5/20 0.53
ALDH1A1 P00352 4/20 0.53
KMT2A Q03164 4/20 0.53
HTT P42858 3/20 0.53
MEN1 O00255 3/20 0.53
TP53 P04637 3/20 0.53
MAPK1 P28482 3/20 0.53
USP2 O75604 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 1/20 0.46
HPGD P15428 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
CYP1A2 P05177 1/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12865181 0.95 LMNA (0.61) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL12325559 0.90 LMNA (0.57) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL14032712 0.90 LMNA (0.56) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL14032760 0.88 LMNA (0.54) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL14032773 0.88 LMNA (0.54) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL12779193 0.86 LMNA (0.53) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL9232165 0.86 LMNA (0.57) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL21469880 0.86 LMNA (0.53) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL14032564 0.86 LMNA (0.57) LMNAKDM4EMAPTALDH1A1KMT2A
SCHEMBL14032735 0.85 ADRB1 (0.56) LMNAKDM4EMAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562817-B1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NAT RECH SCIENT (FR) 2023-11-15 EP disclosed
US-11613513-B2 Organic materials with special optical effects CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-03-28 US disclosed
US-20190337885-A1 Organic Materials with Special Optical Effects CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2019-11-07 US disclosed
EP-3562817-A1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS Centre National de la Recherche Scientifique (CNRS) (FR) 2019-11-06 EP disclosed
CN-110382477-A Organic material with special optical effect 国家科学研究中心 2019-10-25 CN disclosed
WO-2018122359-A1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2018-07-05 WO disclosed
US-20170174689-A1 SUBSTITUTED INDOLE MCL-1 INHIBITORS VANDERBILT UNIVERSITY 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337885-A1 Organic Materials with Special Optical Effects IK, TYR, MITF LMNA 2128/4885KDM4E 3628/4885MAPT 210/4885
US-11613513-B2 Organic materials with special optical effects IK, TYR, MITF LMNA 2128/4885KDM4E 3628/4885MAPT 210/4885
US-20170174689-A1 SUBSTITUTED INDOLE MCL-1 INHIBITORS MCL1, BCL2L1, BCL3 LMNA 3060/4885KDM4E 814/4885MAPT 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.