SCHEMBL1900896

SCHEMBL1900896

Nc1ccc(-c2ccc3cc(-c4ccccc4)ccc3c2)c(N)c1-c1ccc2cc(-c3ccccc3)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
ESR2 Q92731 4/20 0.44
BACE1 P56817 1/20 0.44
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
IKBKB O14920 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1901543 0.90 GSTP1 (0.48) ESR1ESR2ADORA2AADORA1KDM4E
SCHEMBL4450641 0.78 CYP1A1 (0.47) ESR1ESR2ADORA2AADORA1KDM4E
SCHEMBL904407 0.78 ALDH1A1 (0.50) BACE1ADORA2AHSD17B10LMNAMAPT
SCHEMBL22517450 0.77 ADORA2A (0.51) ESR1ESR2BACE1ADORA2AADORA1
SCHEMBL931876 0.76 GSTP1 (0.48) ESR1ESR2ADORA2AADORA1KDM4E
SCHEMBL259164 0.75 GSTP1 (0.47) ESR1ESR2ADORA2AADORA1KDM4E
SCHEMBL28342460 0.75 ESR1 (0.56) ESR1ESR2BACE1KDM4EHSD17B10
SCHEMBL35312 0.74 CYP1A2 (0.52) ESR1ESR2ADORA2AADORA1KDM4E
SCHEMBL9073917 0.73 MAOA (0.48) ESR1ADORA2AKDM4EHSD17B10MEN1
SCHEMBL16107069 0.73 ESR1 (0.73) ESR1ESR2BACE1ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011055932-A9 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-09-01 WO disclosed
WO-2011055932-A2 ORGANIC COMPOUND, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL FOR SAME 덕산하이메탈(주) (KR) 2011-05-12 WO disclosed