Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 6/20 | 0.47 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19523643 | 0.95 | ESR1 (0.52) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL26109085 | 0.89 | ELANE (0.51) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL10036344 | 0.89 | LMNA (0.73) | LMNATYRMAPTHPGDALDH1A1 | |
| SCHEMBL3148686 | 0.89 | LMNA (0.73) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL19517748 | 0.85 | LMNA (0.52) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL3899539 | 0.84 | MEN1 (0.70) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL12805263 | 0.84 | MEN1 (0.70) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL25947115 | 0.83 | LMNA (0.64) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL20793944 | 0.83 | LMNA (0.64) | LMNATYRMAPTHPGDNPC1 | |
| SCHEMBL22001052 | 0.83 | LMNA (0.64) | LMNATYRMAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044249-B1 | POLYARYLENE ETHER SULFONE POLYMERS FOR MEMBRANE APPLICATIONS | BASF SE (DE) | 2017-06-21 | — | — | EP | disclosed |