Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.70 |
| ▸ | LTA4H | P09960 | 6/20 | 0.58 |
| ▸ | BAX | Q07812 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12805263 | 1.00 | MEN1 (0.70) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL11587543 | 0.91 | LTA4H (0.75) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL12895539 | 0.89 | NR1H2 (0.56) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL17066651 | 0.84 | PKM (0.58) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL19008969 | 0.84 | LMNA (0.57) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL3175106 | 0.84 | ESR2 (1.00) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL249169 | 0.84 | ESR2 (1.00) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL7811939 | 0.84 | ESR2 (1.00) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL18198 | 0.84 | ESR2 (1.00) | MEN1KMT2ANR1H2ESR1ESR2 | |
| SCHEMBL10914949 | 0.84 | NR1H2 (1.00) | MEN1KMT2ANR1H2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072002-A2 | BISPHENOLS IN CANCER THERAPY | UNIVERSITY OF MANITOBA (US) | 2009-06-11 | — | — | WO | disclosed |