SCHEMBL19009598

SCHEMBL19009598

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2nc(-c3ccc(-c4ccccn4)cc3)nc(-c3ccc(-c4ccccn4)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
TDP1 Q9NUW8 1/20 0.47
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
TP53 P04637 2/20 0.44
PKM P14618 2/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
KLF5 Q13887 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TRPV1 Q8NER1 2/20 0.43
DHODH Q02127 1/20 0.43
NPC1 O15118 3/20 0.42
CYP2A6 P11509 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13276249 0.92 CYP2A6 (0.47) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17403760 0.90 KAT6A (0.43) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17451985 0.86 CYP2A6 (0.46) KDM4ERAB9ASMN1; SMN2ALDH1A1TP53
SCHEMBL2757062 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2252937 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL19039940 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL19009529 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL17932570 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2253669 0.85 KDM4E (0.59) KDM4ETDP1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13454341 0.85 LMNA (0.46) KDM4ESMN1; SMN2ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170317294-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-02 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179402-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 KDM4E 2540/4885TDP1 3082/4885RAB9A 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.