SCHEMBL19009853

SCHEMBL19009853

O=P(c1ccccc1)(c1ccccc1)c1c2ccccc2c(-c2nc3ccc4cccnc4c3c3c4ccccc4c4ccccc4c23)c2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
CYP3A4 P08684 2/20 0.33
TOP2A P11388 1/20 0.33
KDM4E B2RXH2 4/20 0.32
MAPT P10636 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32
CYP2D6 P10635 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
MMP8 P22894 1/20 0.32
CCR1 P32246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009855 0.86 TYMS (0.35) LMNATOP2AKDM4EMAPTSMN1; SMN2
SCHEMBL19020460 0.84 LMNA (0.37) LMNACYP3A4KDM4EMAPTSMN1; SMN2
SCHEMBL19009821 0.80 NPSR1 (0.36) LMNATOP2AMAPTTSHRTERT
SCHEMBL19009816 0.79 TOP2A (0.33) TOP2AKDM4ESMN1; SMN2ALDH1A1
SCHEMBL20108833 0.76 CCR1 (0.41) LMNACYP3A4KDM4EMAPTSMN1; SMN2
SCHEMBL17997942 0.74 LMNA (0.35) LMNACYP3A4TOP2AKDM4EMAPT
SCHEMBL19009812 0.72 NPSR1 (0.36)
SCHEMBL17034907 0.72 NPSR1 (0.34) LMNACYP3A4TOP2AMAPTTDP1
SCHEMBL17997861 0.72 TOP1 (0.35) LMNATOP2AKDM4EMAPTSMN1; SMN2
SCHEMBL19009820 0.71 NPSR1 (0.32) LMNATP53CYP2D6HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179407-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 LMNA 1959/4885CYP3A4 763/4885TOP2A 2161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.