Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445524 | 0.95 | NPC1 (0.47) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL15457978 | 0.95 | NPC1 (0.47) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL29445525 | 0.95 | NPC1 (0.47) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL19689000 | 0.93 | MAPK1 (0.48) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9160258 | 0.91 | NPC1 (0.53) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL12464280 | 0.91 | MAPK1 (0.44) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL16103701 | 0.89 | MAPK1 (0.43) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL2489704 | 0.89 | RAB9A (0.51) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL29472178 | 0.89 | RAB9A (0.51) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL10040417 | 0.88 | ESR1 (0.45) | NPC1RAB9AMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113233953-B | Method for preparing 2, 6-di-tert-butyl naphthalene with high selectivity by naphthalene alkylation | 浙江大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-113233953-A | Method for preparing 2, 6-di-tert-butyl naphthalene with high selectivity by naphthalene alkylation | 浙江大学 | 2021-08-10 | — | — | CN | disclosed |
| US-20170174995-A1 | COMPOUND AND LIQUID-CRYSTAL COMPOSITION EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-06-22 | — | — | US | disclosed |
| US-20170174994-A1 | COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174995-A1 | COMPOUND AND LIQUID-CRYSTAL COMPOSITION EMPLOYING THE SAME | ZYX, ZRANB2, CXXC4 | NPC1 459/4885RAB9A 2293/4885MAPK1 1726/4885 |
| US-20170174994-A1 | COMPOUND AND LIQUID CRYSTAL COMPOSITION EMPLOYING THE SAME | ZYX, ZRANB2, CXXC4 | NPC1 470/4885RAB9A 2376/4885MAPK1 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.