SCHEMBL29445524

SCHEMBL29445524

CCC(C)(C)c1ccc2cc3cc(C(C)(C)CC)ccc3cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPK1 P28482 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
CASP3 P42574 1/20 0.47
ATM Q13315 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
MAPT P10636 1/20 0.46
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HRH3 Q9Y5N1 8/20 0.37
MAOB P27338 6/20 0.37
CNR2 P34972 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445525 1.00 NPC1 (0.47) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL15457978 1.00 NPC1 (0.47) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL19010378 0.95 NPC1 (0.50) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL2489704 0.94 RAB9A (0.51) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL29472178 0.94 RAB9A (0.51) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL19689000 0.93 MAPK1 (0.48) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL20408452 0.90 NPC1 (0.41) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL20408454 0.89 ESR1 (0.42) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL20408453 0.88 NPC1 (0.42) NPC1RAB9AMAPK1SMN1; SMN2LMNA
SCHEMBL20408440 0.87 KLF10 (0.40) NPC1RAB9AMAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114289061-B Application of catalyst in conversion of disubstituted alkylanthracene into monosubstituted alkylanthracene 浙江恒逸石化研究院有限公司 2024-05-10 CN disclosed
CN-114289061-A Catalyst for converting disubstituted alkyl anthracene into monosubstituted alkyl anthracene and preparation method and application thereof 浙江恒逸石化研究院有限公司 2022-04-08 CN disclosed