SCHEMBL1901192

SCHEMBL1901192

NCCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.70
EPHX2 P34913 1/20 0.51
TLR2 O60603 2/20 0.46
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CASP3 P42574 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29625190 0.99 KMT2A (0.69) KMT2AEPHX2TLR2FABP7FABP5
Hydrochloric Acid SCHEMBL6366017 0.99 KMT2A (0.69) KMT2AEPHX2TLR2FABP7FABP5
Bromide SCHEMBL15809739 0.99 KMT2A (0.69) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL31135496 0.96 KMT2A (0.73) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL5033236 0.96 KMT2A (0.73) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL16297741 0.95 KMT2A (0.65) KMT2AEPHX2TLR2CA1CA2
SCHEMBL15160681 0.95 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL6036899 0.95 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL16379393 0.95 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
Bromide SCHEMBL15809407 0.95 KMT2A (0.71) KMT2AEPHX2TLR2FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 US disclosed
US-20240425517-A1 NOVEL COMPOUND FOR DEGRADATION OF TARGET PROTEIN OR POLYPEPTIDE BY POLYUBIQUITINATION PRAZER THERAPEUTICS INC. (KR) 2024-12-26 US disclosed
EP-4450490-A1 NOVEL COMPOUND FOR DEGRADING TARGET PROTEIN OR POLYPEPTIDE BY USING POLYUBIQUITINATION Prazer Therapeutics Inc. (KR) 2024-10-23 EP disclosed
US-12115224-B2 Polypeptide conjugates for intracellular delivery of stapled peptides OHIO STATE INNOVATION FOUNDATION (US) 2024-10-15 US disclosed
US-12037336-B2 Compounds with activity as inhibitors of the epithelial sodium channel (ENaC) Enterprise Therapeutics Limited (GB) 2024-07-16 US disclosed
US-12037336-B2 Compounds with activity as inhibitors of the epithelial sodium channel (ENaC) Enterprise Therapeutics Limited (GB) 2024-07-16 US disclosed
US-20240067653-A1 BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS Enterprise Therapeutics Limited (GB) 2024-02-29 US disclosed
US-20240067653-A1 BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS Enterprise Therapeutics Limited (GB) 2024-02-29 US disclosed
CN-117567639-A Polypeptide conjugates for intracellular delivery of binding peptides 俄亥俄州国家创新基金会 2024-02-20 CN disclosed
CN-111447941-B Polypeptide conjugates for intracellular delivery of binding peptides 俄亥俄州国家创新基金会 2023-10-31 CN disclosed
US-8546533-B2 Pipecolic linker and its use for chemistry on solid support CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-10-01 US disclosed
WO-2013116682-A1 MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 ENSEMBLE THERAPEUTICS CORPORATION (US) 2013-08-08 WO disclosed
US-20110152464-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT UNIVERSITE DE MONTPELLIER I (FR) 2011-06-23 US disclosed
US-20110152464-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT UNIVERSITE DE MONTPELLIER I (FR) 2011-06-23 US disclosed
EP-2321277-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT Centre National de la Recherche Scientifique - CNRS (FR) 2011-05-18 EP disclosed
WO-2010023295-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-03-04 WO disclosed
US-20080220536-A1 Methods for Identifying Compounds that Modulate Enzymatic Activities by Employing Covalently Bonded Target-Extender Complexes with Ligand Candidates ERIANSON DANIEL A 2008-09-11 US disclosed
US-20080220536-A1 Methods for Identifying Compounds that Modulate Enzymatic Activities by Employing Covalently Bonded Target-Extender Complexes with Ligand Candidates ERIANSON DANIEL A 2008-09-11 US disclosed
US-7214487-B2 Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates SUNESIS PHARMACEUTICALS, INC. (US) 2007-05-08 US disclosed
US-7214487-B2 Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates SUNESIS PHARMACEUTICALS, INC. (US) 2007-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425517-A1 NOVEL COMPOUND FOR DEGRADATION OF TARGET PROTEIN OR POLYPEPTIDE BY POLYUBIQUITINATION ADRM1, SUMO1, SUMO2 KMT2A 2366/4885EPHX2 4171/4885TLR2 3672/4885
US-12037336-B2 Compounds with activity as inhibitors of the epithelial sodium channel (ENaC) SCNN1B, SCNN1A, SCNN1G KMT2A 4545/4885EPHX2 3496/4885TLR2 4589/4885
US-20240067653-A1 BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS NHERF1, SCNN1B, SCNN1A KMT2A 4508/4885EPHX2 3856/4885TLR2 3988/4885
US-20110152464-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT PRRC2C, VIP, PRRC2A KMT2A 4248/4885EPHX2 175/4885TLR2 4645/4885
US-12115224-B2 Polypeptide conjugates for intracellular delivery of stapled peptides VIP, IAPP, TAP1 KMT2A 4716/4885EPHX2 4394/4885TLR2 3273/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS KMT2A 1898/4885EPHX2 4152/4885TLR2 3918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.