SCHEMBL5033236

SCHEMBL5033236

NCCCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.73
EPHX2 P34913 1/20 0.50
TLR2 O60603 2/20 0.47
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
CASP3 P42574 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31135496 1.00 KMT2A (0.73) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL31164313 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL16379393 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL31164312 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL15160681 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL6036899 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
Bromide SCHEMBL15809407 0.99 KMT2A (0.71) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL15160677 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL15155687 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5
SCHEMBL31164311 0.99 KMT2A (0.75) KMT2AEPHX2TLR2FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564650-B2 Carbonic anhydrase IX-targeting radioactive diagnostic and therapeutic medicament and method for preparing same NORROY BIOSCIENCE CO., LTD. (CN) 2026-03-03 US disclosed
US-20240415988-A1 CARBONIC ANHYDRASE IX-TARGETING RADIOACTIVE DIAGNOSTIC AND THERAPEUTIC MEDICAMENT AND METHOD FOR PREPARING SAME NORROY BIOSCIENCE CO., LTD. (CN) 2024-12-19 US disclosed
CN-117186087-A Carbonic anhydrase IX targeted radioactive diagnosis and treatment medicine and preparation method thereof 无锡诺宇医药科技有限公司 2023-12-08 CN disclosed
WO-2023155454-A1 CARBONIC ANHYDRASE IX-TARGETING RADIOACTIVE DIAGNOSTIC AND THERAPEUTIC MEDICAMENT AND METHOD FOR PREPARING SAME 无锡诺宇医药科技有限公司 2023-08-24 WO disclosed
US-20230256080-A1 VACCINE AND THERAPEUTIC COMPOSITIONS COMPRISING ANTIGEN-CONJUGATED VIRAL CAPSIDS UNIV MICHIGAN STATE (US) 2023-08-17 US disclosed
US-11576957-B2 Vaccine and therapeutic compositions comprising antigen-conjugated viral capsids BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2023-02-14 US disclosed
CN-111569083-A Targeting vector suitable for African swine fever virus resistant siRNA (small interfering ribonucleic acid) medicine and application thereof 杭州勇诚睿生物科技有限公司 2020-08-25 CN disclosed
US-20200261559-A1 COMPOSITIONS AND METHODS OF TREATING CANCER AND INFECTIONS USING BACTERIOPHAGE AND ITS MUTANTS BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2020-08-20 US disclosed
CN-111514307-A Novel liver targeting drug carrier 杭州勇诚睿生物科技有限公司 2020-08-11 CN disclosed
EP-3675902-A1 COMPOSITIONS AND METHODS OF TREATING CANCER AND INFECTIONS USING BACTERIOPHAGE AND ITS MUTANTS Board of Trustees of Michigan State University (US) 2020-07-08 EP disclosed
WO-2007005491-A1 HYDRAZIDE CONJUGATES AS IMAGING AGENTS BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2007-01-11 WO disclosed
EP-1740522-A2 BISPHENYL COMPOUNDS USEFUL AS VITAMIN D SB 3 /SB RECEPTOR AGONISTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-01-10 EP disclosed
US-20060025474-A1 Bisphenyl compounds useful as vitamin D3 receptor agonists CHUGAI SEIYAKU KABUSHIKA KAISHA (JP) 2006-02-02 US disclosed
US-6949679-B1 Polyamine transport inhibitors UNIVERSITE LAVAL (CA) 2005-09-27 US disclosed
WO-2005087700-A2 BISPHENYL COMPOUNDS USEFUL AS VITAMIN D3 RECEPTOR AGONISTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2005-09-22 WO disclosed
WO-2000034226-A1 POLYAMINE TRANSPORT INHIBITORS UNIVERSITE LAVAL (CA) 2000-06-15 WO disclosed
EP-1003715-A1 POLYAMINE TRANSPORT INHIBITORS UNIVERSITE LAVAL (CA) 2000-05-31 EP disclosed
WO-1999054283-A1 POLYAMINE TRANSPORT INHIBITORS UNIVERSITE LAVAL (CA) 1999-10-28 WO disclosed
EP-0876327-A2 POLYAMINE TRANSPORT INHIBITORS UNIVERSITE LAVAL (CA) 1998-11-11 EP disclosed
WO-1998017623-A2 POLYAMINE TRANSPORT INHIBITORS UNIVERSITE LAVAL (US) 1998-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200261559-A1 COMPOSITIONS AND METHODS OF TREATING CANCER AND INFECTIONS USING BACTERIOPHAGE AND ITS MUTANTS TP53, COIL, COPE KMT2A 1162/4885EPHX2 4049/4885TLR2 192/4885
US-12564650-B2 Carbonic anhydrase IX-targeting radioactive diagnostic and therapeutic medicament and method for preparing same CA9, CA12, CA13 KMT2A 2644/4885EPHX2 2196/4885TLR2 4498/4885
US-20240415988-A1 CARBONIC ANHYDRASE IX-TARGETING RADIOACTIVE DIAGNOSTIC AND THERAPEUTIC MEDICAMENT AND METHOD FOR PREPARING SAME CA9, CA14, CA13 KMT2A 2087/4885EPHX2 836/4885TLR2 4820/4885
US-20060025474-A1 Bisphenyl compounds useful as vitamin D3 receptor agonists VDR, CYP2R1, CYP24A1 KMT2A 4390/4885EPHX2 2508/4885TLR2 552/4885
US-20230256080-A1 VACCINE AND THERAPEUTIC COMPOSITIONS COMPRISING ANTIGEN-CONJUGATED VIRAL CAPSIDS TP53, LY96, BLK KMT2A 1046/4885EPHX2 4454/4885TLR2 216/4885
US-11576957-B2 Vaccine and therapeutic compositions comprising antigen-conjugated viral capsids TP53, MAPT, SPAG5 KMT2A 1665/4885EPHX2 4357/4885TLR2 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.