SCHEMBL1901202

SCHEMBL1901202

CSCC(O[Si](C)(C)C(C)(C)C)(C(=O)c1ccccc1)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
ENPP1 P22413 2/20 0.41
P2RY1 P47900 1/20 0.41
ADORA1 P30542 2/20 0.41
AHCY P23526 4/20 0.40
GNMT Q14749 2/20 0.39
P2RX3 P56373 1/20 0.38
P2RX4 Q99571 1/20 0.38
P2RX2 Q9UBL9 1/20 0.38
STING1 Q86WV6 2/20 0.38
NT5E P21589 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2835834 0.77 POLB (0.45) POLBENPP1P2RY1ADORA1AHCY
SCHEMBL718524 0.77 POLB (0.45) POLBENPP1P2RY1ADORA1AHCY
SCHEMBL888230 0.76 AHCY (0.46) POLBENPP1P2RY1AHCYSTING1
SCHEMBL715688 0.73 P2RX3 (0.39) POLBADORA1AHCYGNMTP2RX3
SCHEMBL338780 0.71 POLB (0.60) POLBENPP1P2RY1P2RX3P2RX4
SCHEMBL20506692 0.71 ADORA1 (0.42) POLBENPP1P2RY1ADORA1P2RX3
SCHEMBL24370870 0.71 POLB (0.61) POLBENPP1P2RY1ADORA1AHCY
SCHEMBL14208967 0.71 POLB (0.61) POLBENPP1P2RY1ADORA1AHCY
SCHEMBL24370817 0.71 POLB (0.61) POLBENPP1P2RY1ADORA1AHCY
SCHEMBL31098256 0.71 POLB (0.61) POLBENPP1P2RY1ADORA1AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9879309-B2 Methods and compositions for base calling nucleic acids INTELLIGENT BIO-SYSTEMS, INC. (US) 2018-01-30 US disclosed
US-20130301888-A1 Methods And Compositions For Base Calling Nucleic Acids IsoPlexis Corporation 2013-11-14 US disclosed
US-20130137091-A1 Methods And Compositions For Incorporating Nucleotides INTELLIGENT BIO-SYSTEMS, INC. 2013-05-30 US disclosed
US-20110124054-A1 Methods And Compositions For Inhibiting Undesired Cleaving Of Labels INTELLIGENT BIO-SYSTEMS, INC. 2011-05-26 US disclosed