SCHEMBL1901288

SCHEMBL1901288

CC1(C)CC(OC(=O)CCC(=O)O)CC(C)(C)N1CCO

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 3/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
ALDH1A1 P00352 1/20 0.31
APEX1 P27695 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL210915 0.94 SMN1; SMN2 (0.36) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL9659090 0.87 NAAA (0.43) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL27523924 0.86 NAAA (0.40) KMT2AMEN1GAASMN1; SMN2TSHR
SCHEMBL2784913 0.85 NAAA (0.34) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL19648623 0.85 MEN1 (0.31) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL222589 0.84 SMN1; SMN2 (0.36) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL27499875 0.83 TSHR (0.38) SMN1; SMN2TSHRKDM6BKDM5CEGLN1
SCHEMBL3630829 0.81 GAA (0.43) KMT2AMEN1GAATP53SMN1; SMN2
SCHEMBL28783078 0.81 TSHR (0.33) KMT2AMEN1GAATSHRALDH1A1
SCHEMBL2518757 0.80 MMP3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130074930-A1 POLYMETHYL (METH)ACRYLATE MOULDINGS FOR FLUORESCENCE CONVERSION, PRODUCTION OF THESE BY THE SHEET CASTING PROCESS AND USE IN SOLAR COLLECTORS EVONIK ROEHM GMBH (DE) 2013-03-28 US claimed
WO-2023139194-A1 POLYMER FOAMS BASED ON BLENDS OF POLY(VINYLIDENE FLUORIDE) AND POLY(METH)ACRYLIMIDE RÖHM GMBH (DE) 2023-07-27 WO disclosed
WO-2023139195-A1 POLYMER FOAMS BASED ON POLY(METH)ACRYLIMIDE RÖHM GMBH (DE) 2023-07-27 WO disclosed
US-20220332935-A1 Method for sterilization of formed articles made of acrylic-based polymers RÖHM GMBH (DE) 2022-10-20 US disclosed
EP-3898729-A1 ACRYLIC COMPOSITION HAVING AN INCREASED RESISTANCE TO ALCOHOLS, OILS AND FATS Röhm GmbH (DE) 2021-10-27 EP disclosed
WO-2020248514-A1 AGRICULTURAL FILM AND PREPARATION METHOD THEREFOR 宁波先锋新材料股份有限公司 2020-12-17 WO disclosed
CN-110387094-B Agricultural film and preparation method thereof 宁波先锋新材料股份有限公司 2020-09-15 CN disclosed
WO-2020126722-A1 ACRYLIC COMPOSITION HAVING AN INCREASED RESISTANCE TO ALCOHOLS, OILS AND FATS RÖHM GMBH (DE) 2020-06-25 WO disclosed
US-8592525-B2 Composition with increased stress cracking resistance EVONIK RÖHM GMBH (DE) 2013-11-26 US disclosed
US-20130112272-A1 WEATHERING-RESISTANT BACKING FILMS EVONIK RÖHM GMBH (DE) 2013-05-09 US disclosed
US-20130059139-A1 TRANSPARENT, WEATHER-RESISTANT BARRIER FILM HAVING AN IMPROVED BARRIER EFFECT AND SCRATCH RESISTANCE PROPERTIES EVONIK ROEHM GMBH (DE) 2013-03-07 US disclosed
US-20120322932-A1 Composition with increased stress cracking resistance EVONIK ROEHM GMBH (DE) 2012-12-20 US disclosed
US-8227549-B2 Composition with increased stress cracking resistance EVONIK RÖHM GMBH (DE) 2012-07-24 US disclosed
US-8178624-B2 Coloured composition with increased stress cracking resistance EVONIK RÖHM GMBH (DE) 2012-05-15 US disclosed
US-7947781-B2 Polymer mixture consisting of an impact-resistance modified poly (meth) acrylate and a fluoropolymer EVONIK ROHM GMBH (DE) 2011-05-24 US disclosed
US-20100174022-A1 COMPOSITION WITH INCREASED STRESS CRACKING RESISTANCE EVONIK ROEHM GMBH (DE) 2010-07-08 US disclosed
US-20100148401-A1 COLOURED COMPOSITION WITH INCREASED STRESS CRACKING RESISTANCE EVONIK ROEHM GMBH (DE) 2010-06-17 US disclosed
US-20070185270-A1 Polymer mixture consisting of an impact-resistance modified poly (meth) acrylate and a fluoropolymer ROEHM GMBH (DE) 2007-08-09 US disclosed
US-5621028-A THERMOPLASTIC RESIN COMPRISING ULTRAVIOLET ABSORBER, RADICAL SCAVENGER, AND LIGHT SCATTERING, CROSSLINKED, PHENYL-CONTAINING ADDITION POLYMER PARTICLES IN A METHYL METHACRYLATE (CO)POLYMER MATRIX ROEHM GMBH CHEMISCHE FABRIK (DE) 1997-04-15 US disclosed