SCHEMBL1901305

SCHEMBL1901305

O=C(O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648813 0.79 MLYCD (0.62) MLYCD
SCHEMBL650043 0.72 MLYCD (0.56) MLYCD
SCHEMBL1903557 0.72 MLYCD (0.64) MLYCD
SCHEMBL650108 0.70 MLYCD (0.58) MLYCD
SCHEMBL647138 0.69 MLYCD (0.70) MLYCD
SCHEMBL649533 0.66 MLYCD (0.67) MLYCD
SCHEMBL10072178 0.63 MLYCD (0.48) MLYCD
SCHEMBL650069 0.57 MLYCD (0.40) MLYCD
SCHEMBL6314894 0.57 LMNA (0.38)
SCHEMBL1681750 0.56 ALDH1A1 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411929-B1 MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS CHUGAI PHARMACEUTICAL CO LTD (JP) 2011-05-11 EP claimed