Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014710 | 0.81 | LMNA (0.40) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL1442202 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL13725441 | 0.80 | HTT (0.59) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL19014642 | 0.80 | HSD17B10 (0.42) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL12304971 | 0.76 | LMNA (0.58) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL21338346 | 0.76 | LMNA (0.55) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL9932079 | 0.76 | LMNA (0.62) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL27479706 | 0.75 | LMNA (0.57) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL1439677 | 0.75 | LMNA (0.57) | LMNASMN1; SMN2HTTHSD17B10L3MBTL1 | |
| SCHEMBL25851930 | 0.75 | SLC1A3 (0.50) | LMNASMN1; SMN2HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |