Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014642 | 0.86 | HSD17B10 (0.42) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL19014644 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL10251350 | 0.80 | LMNA (0.50) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL1439677 | 0.73 | LMNA (0.57) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL9204222 | 0.72 | LMNA (0.53) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL7282990 | 0.72 | HSD17B10 (0.56) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL9193616 | 0.71 | HTT (0.48) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL24526454 | 0.71 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2L3MBTL1MAPTHTT | |
| SCHEMBL9202853 | 0.71 | HTT (0.55) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT | |
| SCHEMBL9189677 | 0.71 | LMNA (0.44) | LMNASMN1; SMN2HSD17B10L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |