Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014710 | 0.86 | LMNA (0.40) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19014644 | 0.80 | LMNA (0.47) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL1439677 | 0.72 | LMNA (0.57) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9204222 | 0.71 | LMNA (0.53) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL7282990 | 0.70 | HSD17B10 (0.56) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9202853 | 0.69 | HTT (0.55) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL13853971 | 0.69 | HTT (0.58) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL25851930 | 0.69 | SLC1A3 (0.50) | LMNASMN1; SMN2MAPTL3MBTL1HTT | |
| SCHEMBL7283056 | 0.69 | HSD17B10 (0.49) | HSD17B10LMNASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL12304971 | 0.68 | LMNA (0.58) | LMNASMN1; SMN2MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |