Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069175 | 0.81 | TDP1 (0.40) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL19135192 | 0.80 | NOD2 (0.31) | TDP1 | |
| SCHEMBL21201790 | 0.78 | ELANE (0.38) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL18069183 | 0.77 | TDP1 (0.39) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL24225980 | 0.75 | MEN1 (0.31) | MEN1POLBMAPTKMT2AL3MBTL1 | |
| SCHEMBL18069180 | 0.74 | KMT2A (0.48) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL18069178 | 0.74 | MEN1 (0.39) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL18069191 | 0.73 | BRD4 (0.40) | BRD4MEN1RGS12USP2POLB | |
| SCHEMBL22972531 | 0.72 | KDM4E (0.41) | MEN1POLBMAPTHTTKMT2A | |
| SCHEMBL18576631 | 0.72 | MEN1 (0.34) | BRD4MEN1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |