Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23251204 | 0.95 | ALDH1A1 (0.43) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL19015102 | 0.92 | ALDH1A1 (0.44) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL12403339 | 0.90 | ALDH1A1 (0.42) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL12270918 | 0.88 | ALDH1A1 (0.43) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL19015103 | 0.87 | ALDH1A1 (0.40) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL19015299 | 0.85 | ALDH1A1 (0.40) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL19015298 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAALMNANPSR1 | |
| SCHEMBL12510879 | 0.84 | ALDH1A1 (0.40) | ALDH1A1GAALMNANPSR1KDM4E | |
| SCHEMBL12270824 | 0.81 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12227942 | 0.81 | ALDH1A1 (0.43) | ALDH1A1GAALMNANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390348-B1 | DENDRIMER AND FORMULATIONS THEREOF | LOVELAND PRODUCTS INC (US) | 2024-04-17 | — | — | EP | disclosed |
| US-10981858-B2 | Dendrimer and formulations thereof | Priostar Pty Ltd (AU) | 2021-04-20 | — | — | US | disclosed |
| US-10981858-B2 | Dendrimer and formulations thereof | Priostar Pty Ltd (AU) | 2021-04-20 | — | — | US | disclosed |
| US-20180370900-A1 | DENDRIMER AND FORMULATIONS THEREOF | STARPHARMA PTY LTD. (AU) | 2018-12-27 | — | — | US | disclosed |
| WO-2017100856-A1 | DENDRIMER AND FORMULATIONS THEREOF | STARPHARMA PTY LTD (AU) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981858-B2 | Dendrimer and formulations thereof | DDT, PDCD2L, DNM2 | ALDH1A1 683/4885GAA 1132/4885LMNA 3410/4885 |
| US-20180370900-A1 | DENDRIMER AND FORMULATIONS THEREOF | DDT, PDCD2L, DNM2 | ALDH1A1 683/4885GAA 1132/4885LMNA 3410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.