Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015102 | 0.94 | ALDH1A1 (0.44) | ALDH1A1LMNAGAANPSR1KDM4E | |
| SCHEMBL19015299 | 0.93 | ALDH1A1 (0.40) | ALDH1A1LMNAGAANPSR1USP2 | |
| SCHEMBL19015100 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAGAANPSR1KDM4E | |
| SCHEMBL23251204 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAGAANPSR1KDM4E | |
| SCHEMBL12403339 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAGAANPSR1KDM4E | |
| SCHEMBL18296270 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNAGAANPSR1USP2 | |
| SCHEMBL12270918 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAGAANPSR1USP2 | |
| SCHEMBL19015298 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNAGAANPSR1 | |
| SCHEMBL12510879 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAGAANPSR1KDM4E | |
| SCHEMBL757371 | 0.72 | USP2 (0.53) | ALDH1A1LMNAGAANPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100856-A1 | DENDRIMER AND FORMULATIONS THEREOF | STARPHARMA PTY LTD (AU) | 2017-06-22 | — | — | WO | disclosed |