Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 12/20 | 0.44 |
| ▸ | CASP7 | P55210 | 6/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP4 | P49662 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 2/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | CASP5 | P51878 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015922 | 0.87 | CASP3 (0.61) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL18782201 | 0.87 | CASP3 (0.61) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL19015826 | 0.82 | PSMB5 (0.36) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL19015900 | 0.81 | CASP3 (0.51) | CASP3CASP7CASP1CASP4CTSS | |
| SCHEMBL19015923 | 0.78 | CASP3 (0.55) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL18782202 | 0.76 | CASP3 (0.53) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL19015746 | 0.76 | CASP3 (0.59) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL7884220 | 0.75 | CASP3 (0.52) | CASP3CASP7CASP1CASP4CTSS | |
| SCHEMBL19015962 | 0.75 | CASP3 (0.75) | CASP3CASP7CASP1CASP4PSMB5 | |
| SCHEMBL18782011 | 0.75 | CASP3 (0.75) | CASP3CASP7CASP1CASP4PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |