Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.36 |
| ▸ | CASP3 | P42574 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP9 | P55211 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.32 |
| ▸ | CASP5 | P51878 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015746 | 0.82 | CASP3 (0.59) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19015820 | 0.82 | CASP3 (0.44) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19015945 | 0.81 | CASP3 (0.49) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL18782202 | 0.81 | CASP3 (0.53) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL15459253 | 0.80 | PSMB5 (0.44) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19015900 | 0.80 | CASP3 (0.51) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19944840 | 0.78 | PSMB5 (0.63) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19015957 | 0.78 | CASP3 (0.33) | PSMB5CASP3CTSC | |
| SCHEMBL19015827 | 0.77 | CASP3 (0.46) | PSMB5CASP3CASP1CASP9CASP7 | |
| SCHEMBL19015896 | 0.77 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |