Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 17/20 | 0.61 |
| ▸ | CASP7 | P55210 | 12/20 | 0.61 |
| ▸ | CASP1 | P29466 | 6/20 | 0.59 |
| ▸ | CASP9 | P55211 | 4/20 | 0.58 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 2/20 | 0.48 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015963 | 0.85 | CASP3 (0.48) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015930 | 0.77 | CASP3 (0.78) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18782016 | 0.76 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL16376154 | 0.76 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL9961951 | 0.76 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL19015752 | 0.75 | CASP3 (0.79) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18782018 | 0.75 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18472477 | 0.75 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL18471571 | 0.74 | CASP1 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7975479 | 0.74 | CASP1 (1.00) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |