Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 7/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888466 | 0.94 | CASP3 (0.52) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL19015914 | 0.94 | CASP3 (0.52) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL7887042 | 0.90 | CASP3 (0.62) | CASP3CASP1CASP7RENCTSL | |
| SCHEMBL7882928 | 0.87 | CASP3 (0.70) | CASP3CASP1CASP7RENCTSB | |
| SCHEMBL7877666 | 0.84 | CASP3 (0.54) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL7878944 | 0.84 | CTSL (0.52) | CASP3CASP1CASP7ALDH1A1REN | |
| SCHEMBL19015946 | 0.82 | CASP3 (0.60) | CASP3CASP1CASP7RENCTSL | |
| SCHEMBL9961904 | 0.82 | CASP3 (0.61) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL7887265 | 0.82 | CASP3 (0.61) | CASP3CASP1CASP7CTSLCTSB | |
| SCHEMBL18471338 | 0.82 | CASP3 (0.61) | CASP3CASP1CASP7CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133000-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | NEW WORLD LABORATORIES INC. (CA) | 2010-11-25 | — | — | WO | disclosed |