Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231919 | 0.81 | GRIN2D (0.37) | MAPTFFAR1 | |
| SCHEMBL19829195 | 0.80 | KDM1A (0.33) | FFAR1 | |
| SCHEMBL13621692 | 0.74 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL12799721 | 0.74 | MAOB (0.37) | KDM4EALDH1A1POLBGAAKMT2A | |
| SCHEMBL18310450 | 0.73 | PDE3B (0.36) | MAPTFFAR1 | |
| SCHEMBL13049642 | 0.73 | ACHE (0.60) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL22877078 | 0.73 | THRA (0.42) | MAPTKMT2A | |
| SCHEMBL19703009 | 0.73 | MAOB (0.45) | MAPTFFAR1ACHE | |
| SCHEMBL17806146 | 0.73 | THRA (0.42) | — | |
| SCHEMBL130227 | 0.72 | ACHE (0.52) | KDM4EALDH1A1POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102053-A2 | CINNAMIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |