SCHEMBL19829195

SCHEMBL19829195

FCOc1c(F)cc(F)cc1F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.33
FFAR1 O14842 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
IDO1 P14902 4/20 0.31
AGXT P21549 2/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19019341 0.80 KDM4E (0.34) FFAR1
SCHEMBL13621692 0.78 FFAR1 (0.32) FFAR1
SCHEMBL14524684 0.77 HTR2A (0.38) KDM1AFFAR1MAOAMAOB
SCHEMBL17877592 0.75 SCN8A (0.33)
SCHEMBL25650263 0.73 CCNB2 (0.36) KDM1AFFAR1MAOAMAOB
SCHEMBL13614731 0.71 PTPRC (0.40) FFAR1
SCHEMBL2721002 0.70 SOD1 (0.44) IDO1CES2CES1
SCHEMBL13863864 0.69 CES2 (0.33) IDO1AGXTCES2CES1
SCHEMBL17664889 0.69 FFAR1 (0.32) FFAR1
SCHEMBL15781965 0.69 FFAR4 (0.30) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030351-A1 LIQUID CRYSTAL COMPOUND HAVING POLYFLUORO-2-BUTENOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-02-01 US disclosed