SCHEMBL190197

SCHEMBL190197

O=C(O)C(C1=CCCCCCCCC1)=C(C1=CCCCCCCCC1)C1=CCCCCCCCC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 4/20 0.48
HDAC4 P56524 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
HDAC1 Q13547 3/20 0.41
HDAC3 O15379 2/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
CTSK P43235 1/20 0.40
CCR2 P41597 1/20 0.34
ACMSD Q8TDX5 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066611 1.00 HDAC2 (0.48) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL190196 1.00 HDAC2 (0.48) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL8939554 0.81 HDAC2 (0.54) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL8939555 0.81 HDAC2 (0.54) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL10717487 0.81 THRB (0.37) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL492236 0.79 HDAC4 (0.41) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL6231036 0.79 HDAC2 (0.52) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL2240854 0.79 HDAC2 (0.52) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL1628262 0.77 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1
SCHEMBL518453 0.77 HDAC2 (0.57) HDAC2HDAC4HDAC8HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274385-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYMER COMPOSITIONS WITH OPTIMIZED DEGREE OF CROSSLINKING INEOS Styrolution Group GmbH (DE) 2018-01-31 EP claimed
EP-3074439-B1 THERMOPLASTIC MOULDING COMPOSITIONS WITH APPROPRIATELY DESIGNED GRAFT SHELL INEOS STYROLUTION GROUP GMBH (DE) 2017-10-11 EP claimed
EP-3074439-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH APPROPRIATELY DESIGNED GRAFT SHELL Styrolution Group GmbH (DE) 2016-10-05 EP claimed
WO-2016150999-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYMER COMPOSITIONS WITH OPTIMIZED DEGREE OF CROSSLINKING INEOS STYROLUTION GROUP GMBH (DE) 2016-09-29 WO claimed
WO-2015078751-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH APPROPRIATELY DESIGNED GRAFT SHELL STYROLUTION GROUP GMBH (DE) 2015-06-04 WO claimed
EP-1137680-B1 EMULSION POLYMERIZED POLYACRYLATE RUBBER, IMPACT MODIFIERS AND BLENDS OBTAINED THEREFROM, AND METHOD FOR MAKING GEN ELECTRIC (US) 2005-08-17 EP claimed
WO-2000047675-A1 THERMOPLASTIC MOLDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO claimed
WO-2000047673-A1 THERMOPLASTIC MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO claimed
WO-2000047672-A1 THERMOPLASTIC MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO claimed
WO-2000047674-A1 THERMOPLASTIC MOULDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 2000-08-17 WO claimed
EP-0675164-B1 Thermoplastic moulding compositions from a graft copolymer and an olefine copolymer BASF AG (DE) 1998-05-20 EP claimed
EP-0675164-A1 Thermoplastic moulding compositions from a graft copolymer and an olefine copolymer BASF AKTIENGESELLSCHAFT (DE) 1995-10-04 EP claimed
EP-0244857-B1 THERMOPLASTIC MOULDING COMPOSITION BASED ON POLYCARBONATE, TWO GRAFT COPOLYMERS WITH DIFFERENT GRAFT BASES (ASA + AES) AND COPOLYMERS CONTAINING VINYL AROMATICS AND AN BASF Aktiengesellschaft (DE) 1991-04-10 EP claimed
US-4423187-A IMPACT RESISTANT POLYSTYRENE AND POLYPHENYLENE ETHERS BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US claimed
EP-4554989-B1 METHOD FOR PRODUCING ASA OR ABS GRAFT COPOLYMERS WITH REDUCED DISCOLORATION INEOS STYROLUTION GROUP GMBH (DE) 2026-02-18 EP disclosed
EP-4554990-B1 METHOD FOR PRODUCING ASA OR ABS GRAFT COPOLYMERS WITH REDUCED DISCOLORATION INEOS STYROLUTION GROUP GMBH (DE) 2026-01-14 EP disclosed
EP-4554990-A1 METHOD FOR PRODUCING ASA OR ABS GRAFT COPOLYMERS WITH REDUCED DISCOLORATION INEOS Styrolution Group GmbH (DE) 2025-05-21 EP disclosed
EP-0056964-A2 Thermoplastic moulding masses comprising a styrene polymer, a grafted polyacrylat and a polyphenylene ether BASF Aktiengesellschaft (DE) 1982-08-04 EP disclosed
EP-0006503-B1 WEATHER-PROOF AND IMPACT-RESISTANT THERMOPLASTIC COMPOSITIONS WITH GOOD DYEABILITY, THEIR USE AND SHAPED ARTICLES OBTAINED THEREBY BASF Aktiengesellschaft (DE) 1982-07-28 EP disclosed
EP-0006503-A1 Weather-proof and impact-resistant thermoplastic compositions with good dyeability, their use and shaped articles obtained thereby BASF Aktiengesellschaft (DE) 1980-01-09 EP disclosed