Methacrylic Acid

Methacrylic Acid

SCHEMBL19019784

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(C)(O)CCCCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.41
CYP4A11 Q02928 2/20 0.41
FFAR1 O14842 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CPT2 P23786 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
TET2 Q6N021 1/20 0.34
ALDH1A1 P00352 1/20 0.33
ARG2 P78540 1/20 0.33
ACLY P53396 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6829114 1.00 CYP4F2 (0.41) CYP4F2CYP4A11FFAR1TDP1CPT2
Methacrylic Acid SCHEMBL19019781 0.98 CYP4F2 (0.38) CYP4F2CYP4A11FFAR1TDP1CPT2
Methacrylic Acid SCHEMBL1162380 0.96 TET2 (0.36) CYP4F2CYP4A11FFAR1TDP1CPT2
Methacrylic Acid SCHEMBL7701380 0.92 TDP1 (0.41) FFAR1TDP1CPT2TET2ALDH1A1
Methacrylic Acid SCHEMBL7706294 0.92 TDP1 (0.41) FFAR1TDP1CPT2TET2ALDH1A1
Methacrylic Acid SCHEMBL7709315 0.92 TDP1 (0.41) FFAR1TDP1CPT2TET2ALDH1A1
Methacrylic Acid SCHEMBL7706307 0.90 ALDH1A1 (0.41) FFAR1TDP1CPT2TET2ALDH1A1
Methacrylic Acid SCHEMBL7701346 0.86 ALDH1A1 (0.41) FFAR1TDP1CPT2TET2ALDH1A1
Methacrylic Acid SCHEMBL1960828 0.84 ALDH1A1 (0.39) TDP1TET2ALDH1A1
Methacrylic Acid SCHEMBL22554401 0.83 GPR84 (0.48) CYP4F2CYP4A11FFAR1TDP1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428664-B Method for producing (meth) acrylate compound 株式会社可乐丽 2020-07-10 CN disclosed
CN-107849203-B (meth) acrylic block copolymer 株式会社可乐丽 2020-04-24 CN disclosed
EP-3327053-B1 (METH)ACRYLIC BLOCK COPOLYMER KURARAY CO (JP) 2020-03-25 EP disclosed
US-10426712-B2 Dental polymerizable composition KURARAY NORITAKE DENTAL INC. (JP) 2019-10-01 US disclosed
EP-3269701-B1 METHOD FOR PRODUCING (METH)ACRYLATE ESTER COMPOUNDS KURARAY CO (JP) 2019-05-08 EP disclosed
US-20180208700-A1 (METH)ACRYLIC BLOCK COPOLYMER KURARAY CO., LTD. (JP) 2018-07-26 US disclosed
EP-3327053-A1 (METH)ACRYLIC BLOCK COPOLYMER Kuraray Co., Ltd. (JP) 2018-05-30 EP disclosed
CN-107849203-A (meth) acrylic block copolymer 株式会社可乐丽 2018-03-27 CN disclosed
US-20170290746-A1 DENTAL POLYMERIZABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2017-10-12 US disclosed
US-20170240739-A1 ACTIVE ENERGY RAY CURABLE COMPOSITIONS KURARAY CO., LTD. (JP) 2017-08-24 US disclosed
EP-3195846-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2017-07-26 EP disclosed
EP-3184563-A1 ACTIVE ENERGY RAY-CURABLE COMPOSITION Kuraray Co., Ltd. (JP) 2017-06-28 EP disclosed
CN-106574029-A Active energy ray-curable composition 株式会社可乐丽 2017-04-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10426712-B2 Dental polymerizable composition MMAB, GRIN2B, CAD CYP4F2 4227/4885CYP4A11 4597/4885FFAR1 740/4885
US-20170290746-A1 DENTAL POLYMERIZABLE COMPOSITION MMAB, GRIN2B, CAD CYP4F2 4227/4885CYP4A11 4597/4885FFAR1 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.