Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356318 | 0.91 | TAAR1 (0.43) | SMN1; SMN2NPC1RAB9ACA1CA2 | |
| SCHEMBL22001798 | 0.91 | TAAR1 (0.43) | SMN1; SMN2NPC1RAB9ACA1CA2 | |
| SCHEMBL17615149 | 0.91 | TAAR1 (0.43) | SMN1; SMN2NPC1RAB9ACA1CA2 | |
| SCHEMBL19318327 | 0.91 | TAAR1 (0.43) | SMN1; SMN2NPC1RAB9ACA1CA2 | |
| SCHEMBL22001712 | 0.83 | REN (0.40) | MMP3SMN1; SMN2NPC1RAB9AMMP8 | |
| SCHEMBL19019945 | 0.82 | MMP3 (0.52) | MMP3SMN1; SMN2NPC1RAB9AECE1 | |
| SCHEMBL19375757 | 0.81 | NAMPT (0.43) | MMP3SMN1; SMN2NPC1RAB9AECE1 | |
| SCHEMBL12683445 | 0.80 | CIT (0.43) | CA1CA2ACESPHK1MEN1 | |
| SCHEMBL24797595 | 0.79 | SPHK1 (0.51) | SMN1; SMN2CA1CA2SPHK1 | |
| SCHEMBL22002009 | 0.79 | BACE1 (0.33) | SMN1; SMN2NPC1RAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184540-A1 | SPECIFICALLY ACTIVATED MICROMOLECULAR TARGET COUPLING BODY IN TUMOR MICROENVIRONMENT AND USE THEREOF | Yafei Shanghai Biolog Medicine Science& Technology (CN) | 2017-06-28 | — | — | EP | disclosed |