Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KCNQ3 | O43525 | 17/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 17/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 13/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 13/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898437 | 0.84 | NPC1 (0.78) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1898884 | 0.82 | NPC1 (0.78) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1898341 | 0.81 | NPC1 (0.76) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13757469 | 0.79 | NPC1 (0.78) | RAB9ANPC1MAPT | |
| SCHEMBL15221541 | 0.79 | NPC1 (0.62) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL4255748 | 0.78 | NPC1 (0.67) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7744337 | 0.77 | RAB9A (0.49) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL14340260 | 0.76 | KCNQ3 (0.54) | RAB9AMAPTKCNQ3KCNQ2KCNE1 | |
| SCHEMBL4255743 | 0.76 | NPC1 (0.64) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL2300416 | 0.75 | NPC1 (1.00) | RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-B1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UCL BUSINESS PLC (GB) | 2011-05-04 | — | — | EP | disclosed |