Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chloroaniline SCHEMBL7744755 | 0.85 | NPC1 (0.53) | RAB9ANPC1MAPTRPA1HTR2A | |
| SCHEMBL574266 | 0.80 | NPC1 (0.60) | RAB9ANPC1MAPTALDH1A1RPA1 | |
| SCHEMBL1902091 | 0.77 | RAB9A (0.67) | RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7746867 | 0.76 | NPC1 (0.58) | RAB9ANPC1MAPTALDH1A1GAA | |
| SCHEMBL7744751 | 0.75 | RAB9A (0.51) | RAB9ANPC1MAPTRPA1HTR2A | |
| SCHEMBL3056530 | 0.72 | NPC1 (0.59) | RAB9ANPC1MAPTALDH1A1HTR2A | |
| SCHEMBL14351864 | 0.69 | NPC1 (0.55) | RAB9ANPC1MAPTALDH1A1HTR2A | |
| SCHEMBL2361385 | 0.68 | LMNA (0.67) | PTGER1LMNA | |
| SCHEMBL17321501 | 0.67 | NPC1 (0.52) | RAB9ANPC1MAPTALDH1A1HTR2A | |
| SCHEMBL7746860 | 0.67 | NPC1 (0.56) | RAB9ANPC1MAPTALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | University College London (GB) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057024-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UNIVERSITY COLLEGE LONDON (GB) | 2001-08-09 | — | — | WO | disclosed |