Resveratrol

Resveratrol

SCHEMBL19022437

NC(N)C(=O)O.Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.68
PTGS1 P23219 4/20 0.68
KDM4E B2RXH2 3/20 0.68
LMNA P02545 3/20 0.68
CA12 O43570 3/20 0.68
CA1 P00915 3/20 0.68
CA2 P00918 3/20 0.68
CA3 P07451 3/20 0.68
CA4 P22748 3/20 0.68
CA6 P23280 3/20 0.68
CA5A P35218 3/20 0.68
CA7 P43166 3/20 0.68
CA9 Q16790 3/20 0.68
CA14 Q9ULX7 3/20 0.68
CA5B Q9Y2D0 3/20 0.68
TTR P02766 3/20 0.68
CYP1A1 P04798 3/20 0.68
CYP1B1 Q16678 3/20 0.68
CA13 Q8N1Q1 2/20 0.68
MEN1 O00255 2/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol SCHEMBL27883730 0.87 PTGS2 (0.76) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL28719858 0.87 PTGS2 (0.83) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL19331476 0.86 PTGS2 (0.68) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL28030055 0.83 PTGS2 (0.76) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL21225662 0.83 PTGS2 (0.76) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL29473334 0.83 PTGS2 (0.76) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL19209911 0.83 SLC7A5 (0.69) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL19209910 0.83 SLC7A5 (0.69) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL28307179 0.82 KDM4E (0.91) PTGS2PTGS1KDM4ELMNACA12
Resveratrol SCHEMBL19426 0.82 PTGS1 (1.00) PTGS2PTGS1KDM4ELMNACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190241498-A1 RESVERATROL ESTERS COLE RES & DESIGN LLC (US) 2019-08-08 US disclosed
US-10099995-B2 Resveratrol esters Cole Research and Design, LLC (US) 2018-10-16 US disclosed
WO-2018164662-A1 RESVERATROL ESTERS ELSOHLY MAHMOUD A (US) 2018-09-13 WO disclosed
US-20170183290-A1 RESVERATROL ESTERS COLE RESEARCH & DESIGN, LLC. 2017-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241498-A1 RESVERATROL ESTERS HCAR1, HCAR3, HCAR2 PTGS2 3131/4885PTGS1 2487/4885KDM4E 270/4885
US-20170183290-A1 RESVERATROL ESTERS HCAR1, HCAR3, HCAR2 PTGS2 3131/4885PTGS1 2487/4885KDM4E 270/4885
US-10099995-B2 Resveratrol esters HCAR1, HCAR3, HCAR2 PTGS2 3131/4885PTGS1 2487/4885KDM4E 270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.