Cyclooctene

Cyclooctene

SCHEMBL19026366

C1=C\CCCCCC/1.CCC1CCCCC1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
SHBG P04278 1/20 0.32
ACHE P22303 1/20 0.31
CHRM5 P08912 2/20 0.31
ADRA2C P18825 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclooctene SCHEMBL19026367 1.00 CYP1A2 (0.41) CYP1A2SHBGACHECHRM5ADRA2C
SCHEMBL7980378 0.86 CYP1A2 (0.33) CYP1A2
SCHEMBL9658057 0.86 CYP1A2 (0.33) CYP1A2
SCHEMBL7994796 0.85 CYP1A2 (0.31) CYP1A2
SCHEMBL25446788 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C
SCHEMBL1437788 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C
Cyclohexane SCHEMBL8731700 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C
SCHEMBL18481332 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C
SCHEMBL4576671 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C
SCHEMBL18078965 0.84 CYP1A2 (0.52) CYP1A2SHBGACHECHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220048-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2022-07-14 US disclosed
US-10781150-B2 Molecular sieves mediated unsaturated hydrcarbon separation and related compositions, materials, methods and systems CALIFORNIA INSTITUTE TECHNOLOGY (US) 2020-09-22 US disclosed
US-10427995-B2 Molecular sieves mediated unsaturated hydrocarbon separation and related compositions, materials, methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-10-01 US disclosed
US-20190100480-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDRCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-04-04 US disclosed
EP-3394012-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-10-31 EP disclosed
US-10112878-B2 Molecular sieves mediated unsaturated hydrocarbon separation and related compositions, materials, methods and systems CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-10-30 US disclosed
US-20170183277-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2017-06-29 US disclosed
WO-2017112961-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10112878-B2 Molecular sieves mediated unsaturated hydrocarbon separation and related compositions, materials, methods and systems ORAI2, CACNG8, TRPA1 CYP1A2 2188/4885SHBG 1743/4885ACHE 4747/4885
US-10781150-B2 Molecular sieves mediated unsaturated hydrcarbon separation and related compositions, materials, methods and systems ORAI2, CACNG8, KCNJ2 CYP1A2 2636/4885SHBG 1683/4885ACHE 4738/4885
US-20220220048-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS ORAI2, CACNG8, ORAI3 CYP1A2 1977/4885SHBG 1847/4885ACHE 4722/4885
US-10427995-B2 Molecular sieves mediated unsaturated hydrocarbon separation and related compositions, materials, methods and systems ORAI2, CACNG8, TRPA1 CYP1A2 1997/4885SHBG 1687/4885ACHE 4736/4885
US-20170183277-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDROCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS ORAI2, ORAI3, KCNJ2 CYP1A2 2266/4885SHBG 1879/4885ACHE 4757/4885
US-20190100480-A1 MOLECULAR SIEVES MEDIATED UNSATURATED HYDRCARBON SEPARATION AND RELATED COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS ORAI2, CACNG8, KCNJ2 CYP1A2 2519/4885SHBG 1680/4885ACHE 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.