Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200673 | 0.90 | CRBN (0.60) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL3544056 | 0.90 | CRBN (0.60) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL632914 | 0.90 | CRBN (0.60) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL27647404 | 0.82 | NAAA (0.55) | NAAAALDH1A1GAACTSLTSHR | |
| SCHEMBL5180974 | 0.79 | NAAA (0.58) | NAAAALDH1A1GAACTSLTSHR | |
| SCHEMBL3930648 | 0.79 | NAAA (0.58) | NAAAALDH1A1GAACTSLTSHR | |
| SCHEMBL765661 | 0.79 | NAAA (0.58) | NAAAALDH1A1GAACTSLTSHR | |
| SCHEMBL20812785 | 0.79 | EPHX2 (0.47) | CRBNDDB1NAAAALDH1A1 | |
| SCHEMBL24818238 | 0.77 | CRBN (0.53) | CRBNDDB1GAATSHR | |
| SCHEMBL4394120 | 0.77 | CRBN (0.46) | CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050962-A1 | ACID ADDITION SALTS OF LENALIDOMIDE | RATIOPHARM GMBH (DE) | 2011-05-05 | — | — | WO | disclosed |