Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.60 |
| ▸ | NAAA | Q02083 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544056 | 1.00 | CRBN (0.60) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL632914 | 1.00 | CRBN (0.60) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL1903249 | 0.90 | CRBN (0.53) | CRBNDDB1NAAAALDH1A1GAA | |
| SCHEMBL5180974 | 0.87 | NAAA (0.58) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL3930648 | 0.87 | NAAA (0.58) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL765661 | 0.87 | NAAA (0.58) | NAAAALDH1A1GAATSHRASAH1 | |
| SCHEMBL19207870 | 0.85 | RIPK1 (0.57) | NAAAALDH1A1GAATSHR | |
| SCHEMBL1976229 | 0.85 | RIPK1 (0.57) | NAAAALDH1A1GAATSHR | |
| SCHEMBL7426649 | 0.85 | RIPK1 (0.57) | NAAAALDH1A1GAATSHR | |
| SCHEMBL425375 | 0.82 | ALDH1A1 (0.58) | NAAAALDH1A1GAATSHRCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353672-B1 | SYNTHESIS OF 4-AMINO-THALIDOMIDE ENANTIOMERS | CHILDRENS MEDICAL CENTER (US) | 2007-10-03 | — | — | EP | claimed |
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |