Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901571 | 0.90 | ALDH1A1 (0.38) | FFAR2ALDH1A1MEN1LMNAHTT | |
| SCHEMBL1932231 | 0.88 | FFAR2 (0.38) | FFAR2 | |
| SCHEMBL1903337 | 0.88 | L3MBTL1 (0.43) | FFAR2MEN1LMNAKMT2A | |
| SCHEMBL1932705 | 0.85 | CNR1 (0.40) | FFAR2ALDH1A1MEN1LMNAHTT | |
| SCHEMBL6902839 | 0.84 | ALDH1A1 (0.35) | FFAR2ALDH1A1MEN1LMNAHTT | |
| SCHEMBL1932244 | 0.82 | L3MBTL1 (0.36) | FFAR2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1932519 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1903267 | 0.81 | MEN1 (0.35) | FFAR2ALDH1A1MEN1LMNAHTT | |
| SCHEMBL1931871 | 0.81 | GAA (0.33) | FFAR2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL1932028 | 0.79 | SMN1; SMN2 (0.34) | FFAR2ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493845-B1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER IP GMBH (DE) | 2013-12-25 | — | — | EP | disclosed |
| EP-2493845-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051165-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | WO | disclosed |